Global Journal of Medical and Health Science

THYROID FUNCTION TEST EVALUATION IN PROSTATE CANCER PATIENTS IN KHARTOUM STATE

Authors

  • Abdallah E. Ali University of Alzaeim Al Azhari Faculty of Medical Laboratory Sciences, Department of Clinical Chemistry
  • Sejood E. M. Abdalla University of Alzaeim Al Azhari Faculty of Medical Laboratory Sciences, Department of Clinical Chemistry
  • Ibrahim A. A. Karti Alofoug College of Science & Technology, Program of Medicine, Khartoum, Sudan.
  • Haidar E. Saleh Miami University, Sylvester Comprehensive Cancer Center (SCCC) Clinical Research Laboratory Services Miami Fl33136 USA

Abstract

Introduction: Thyroid hormones (TH) are key regulators of essential cellular processes, including proliferation, differentiation, apoptosis, and metabolism. Thyroid hormones have an important role in the development of prostate cancer. So this study aims to assess thyroid function tests among prostatic cancer patients.

methods: Total group study100, fifty Prostatic cancer patients as a case study and 50 healthy men as the control group, blood samples were collected for measurement for thyroid function test and Prostate Antigen by Tosoh TM device (China) and enzyme-linked immune sorbent assay (ELISA) Fortress TM.                       Results: Statistical analysis of test results of the case study: the mean and SD±   PSA= (31.8 ± 12.5 ) , T3 = (3.3 ± 1.3) , T4 = (119.58 ± 46.21 ) and TSH =(4.6 ± 3.4) . For each P-value 0.0001 when compared to the control group, the frequency of thyroid disorders among case study participants is hyperthyroidism (33 = 66%), normal (14 = 28%), and hypothyroidism (3 = 6%).

 Conclusion: Hyperthyroidism is the most common thyroid disorder among patients with prostatic cancer.

Keywords:

Prostate cancer, Thyroid hormones, T3, T4, TSH, Prostate Antigen

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Published

2023-02-22

Issue

Vol. 1 No. 1: February, 2023

Section

Articles

How to Cite

Ali, A. E., Abdalla, S. E. M., Karti, I. A. A., & Saleh, H. E. (2023). THYROID FUNCTION TEST EVALUATION IN PROSTATE CANCER PATIENTS IN KHARTOUM STATE. Global Journal of Medical and Health Science, 1(1), 17–25. Retrieved from https://zapjournals.com/Journals/index.php/Medical-Health/article/view/66

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