LIFESTYLE INTERVENTIONS FOR MANAGING TYPE-2 DIABETES MELLITUS IN INDONESIA
Abstract
Type-2 diabetes mellitus (T2DM) has reached epidemic proportions in Indonesia, and the World Health Organization (WHO) has projected a significant increase in its prevalence by 2030. This alarming rise is largely attributed to lifestyle factors, including dietary habits and physical inactivity, which influence cell metabolism and DNA methylation, ultimately leading to insulin resistance. As a result, effective management strategies for T2DM must focus on proper dietary regulation and incorporating regular, measurable exercise.
The mechanisms underlying insulin resistance are multifaceted and involve disturbances in cellular metabolism. Consequently, lifestyle interventions play a pivotal role in the management of T2DM. American Diabetes Care has endorsed aerobic exercise as a beneficial approach for individuals with type 2 diabetes, highlighting its significance in enhancing insulin sensitivity and glucose control. Aerobic exercise can be implemented in either a continuous or interval format, offering flexibility to individuals seeking to manage their T2DM.
This paper seeks to explore the impact of lifestyle interventions, particularly dietary modifications and physical activity, in addressing the T2DM epidemic in Indonesia. It delves into the intricate relationship between lifestyle choices and insulin resistance, shedding light on how changes in diet and increased physical activity influence cell metabolism and DNA methylation. The interplay of these factors underscores the importance of a comprehensive approach to T2DM management.
