Contemporary Journal of Advancement in Food Science and Technology (CJAFST)

ADVANCING RACTOPAMINE DETECTION METHODS: IMMUNOAFFINITY COLUMN CLEANUP IN ELISA FOR SWINE TISSUES

Authors

  • Anna van der Berg Professor, Cell Biology and Immunology Group, Wageningen University, The Netherlands
  • Li Ming Research Scientist, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China

Abstract

The misuse of agonists as growth promoters in meat-producing animals has raised significant concerns over the past two decades. Ractopamine (RCT) has emerged as a prominent agonist substance, illicitly employed for enhancing leanness in animals. Despite being approved by regulatory agencies such as the U.S. Food and Drug Administration (FDA) and various authorities in Brazil, Venezuela, Colombia, Guatemala, Dominican Republic, and the Philippines for swine feed, phenethanolamine agonists like RCT have a history of unauthorized usage by livestock producers. This unauthorized use poses potential food safety risks due to the presence of drug residues in animal tissues, particularly when the compound is administered illegally or not in accordance with regulatory guidelines.

The positive impact of ractopamine hydrochloride on economically significant traits makes it an appealing product for swine growers and producers of other livestock species. However, concerns persist regarding the safety and legality of its use, particularly in the context of food safety. Thus, there is a pressing need for comprehensive research and regulatory measures to address the challenges associated with the unauthorized use of RCT and other agonists in meat production.

Keywords:

Agonists, Ractopamine, Meat-producing animals, Food safety, Regulatory compliance

Published

2024-02-20

DOI:

https://doi.org/10.5281/zenodo.10683342

How to Cite

Berg , A. van der, & Li, M. (2024). ADVANCING RACTOPAMINE DETECTION METHODS: IMMUNOAFFINITY COLUMN CLEANUP IN ELISA FOR SWINE TISSUES. Contemporary Journal of Advancement in Food Science and Technology (CJAFST), 10(1), 27–35. https://doi.org/10.5281/zenodo.10683342

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