EFFECT OF PETROLEUM PRODUCT INHALATION ON THE BEHAVIORAL INDICES OF MALE WISTAR RATS
Abstract
Petroleum products are ubiquitous in modern society, and inhalation exposure represents a significant route of potential neurotoxicity. This study analyzed the effect of petroleum product inhalation on the behavioral indices of male Wistar albino rats. Forty-five rats aged 3 months and weighing 180–220 g were divided into five groups: Group A (Control), Group B (PMS exposure - 500 ml), Group C (Kerosene exposure - 500 ml), Group D (Diesel exposure - 500 ml), and Group E (Mixed petroleum products - 500 ml). The exposure lasted for 28 days. Anxiety and cognitive tests were performed. The results of the behavioral indices showed a slight cognitive decline in rats exposed to diesel after 14 days, and petroleum products caused anxiety-like behavior in rats. These results emphasize the harmful effects of inhaling petroleum products on critical organ systems, particularly the brain and lungs
Keywords:
Anxiety, Cognitive test, Petroleum products, Neurotoxicity, Behavioral indices, Y-mazeDownloads
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https://doi.org/10.5281/zenodo.15274227Issue
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Copyright (c) 2025 Edoga, Cyril Onyekachi, Offor, Amarachukwu Grace , Okeke, Chukwuemeka Christian
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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