International Journal of Allied Sciences (IJAS)

EFFECT OF PETROLEUM PRODUCT INHALATION ON THE BEHAVIORAL INDICES OF MALE WISTAR RATS

Authors

  • Edoga, Cyril Onyekachi Department of Applied Biology and Biotechnology, Enugu State University of Science and Technology (ESUT), Enugu Nigeria.
  • Offor, Amarachukwu Grace Department of Applied Biology and Biotechnology, Enugu State University of Science and Technology (ESUT), Enugu Nigeria.
  • Okeke, Chukwuemeka Christian Department of Applied Biology and Biotechnology, Enugu State University of Science and Technology (ESUT), Enugu Nigeria.

Abstract

Petroleum products are ubiquitous in modern society, and inhalation exposure represents a significant route of potential neurotoxicity. This study analyzed the effect of petroleum product inhalation on the behavioral indices of male Wistar albino rats. Forty-five rats aged 3 months and weighing 180–220 g were divided into five groups: Group A (Control), Group B (PMS exposure - 500 ml), Group C (Kerosene exposure - 500 ml), Group D (Diesel exposure - 500 ml), and Group E (Mixed petroleum products - 500 ml). The exposure lasted for 28 days. Anxiety and cognitive tests were performed. The results of the behavioral indices showed a slight cognitive decline in rats exposed to diesel after 14 days, and petroleum products caused anxiety-like behavior in rats. These results emphasize the harmful effects of inhaling petroleum products on critical organ systems, particularly the brain and lungs

Keywords:

Anxiety, Cognitive test, Petroleum products, Neurotoxicity, Behavioral indices, Y-maze

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Published

2025-04-24

DOI:

https://doi.org/10.5281/zenodo.15274227

Issue

Vol. 16 No. 4 (2025): April

Section

Articles

How to Cite

Edoga, C. O., Offor, A. G., & Okeke, C. C. (2025). EFFECT OF PETROLEUM PRODUCT INHALATION ON THE BEHAVIORAL INDICES OF MALE WISTAR RATS. International Journal of Allied Sciences (IJAS), 16(4), 1–6. https://doi.org/10.5281/zenodo.15274227

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Copyright (c) 2025 Edoga, Cyril Onyekachi, Offor, Amarachukwu Grace , Okeke, Chukwuemeka Christian

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

References

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